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Article

Common DNA sequence variation influences 3-dimensional conformation of the human genome

2019-03-30

Abstract excerpt

<h4>ABSTRACT</h4> The 3-dimensional (3D) conformation of chromatin inside the nucleus is integral to a variety of nuclear processes including transcriptional regulation, DNA replication, and DNA damage repair. Aberrations in 3D chromatin conformation have been implicated in developmental abnormalities and cancer. Despite the importance of 3D chromatin conformation to cellular function and human health, little is...

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Literature Corpus work
ba5a8841-ca24-5173-8695-2e13e9791837
DOI
10.1101/592741
Open publication

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Common DNA sequence variation influences 3-dimensional conformation of the human genomeDOI 10.1101/592741
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