Article
3DIV: A 3D-genome Interaction Viewer and database.
Nucleic acids research - 4 Jan 2018
Yang Dongchan, Jang Insu, Choi Jinhyuk, Kim Min-Seo, Lee Andrew J, Kim Hyunwoong, Eom Junghyun, Kim Dongsup, Jung Inkyung, Lee Byungwook
Abstract excerpt
Three-dimensional (3D) chromatin structure is an emerging paradigm for understanding gene regulation mechanisms. Hi-C (high-throughput chromatin conformation capture), a method to detect long-range chromatin interactions, allows extensive genome-wide investigation of 3D chromatin structure. However, broad application of Hi-C data have been hindered by the level of complexity in processing Hi-C data and the large...
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