Article

Multimodal Hypersampling of the adult human heart resolves tissue-specific cell states and disease-associated variants

2026-06-17

Abstract excerpt

Cardiovascular diseases often arise in anatomically specialised regions of the heart that remain poorly represented in existing single-cell and spatial atlas references. Here we profiled 28 regions of the adult human heart from 36 donors, combining paired single-nucleus RNA and chromatin accessibility assays with spatial transcriptomics. The resulting atlas integrates 1,059,175 expression profiles and 452,614 chro...

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Literature Corpus work: ff9ddfa2-f623-5efb-b75a-c9b43e06490a
DOI: 10.64898/2026.06.16.732617

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