Article

Multimodal atlas of human atherosclerosis links granular vascular cell states to coronary artery disease risk

2026-05-26

Abstract excerpt

Advances in single-cell and spatial assays have revolutionized the scale and resolution of molecular tissue profiling. Here we present MetaPlaq, a multimodal atlas of human atherosclerotic arterial beds comprising over a million cells across single-cell transcriptomics, epigenomics and high-resolution spatial expression assays. We map granular cell states and disease-relevant transcriptional programs within the na...

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Literature Corpus work: aee731f0-1695-547b-ab6d-e3fec5915ad3
DOI: 10.64898/2026.05.24.26353986

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