Article

Dissecting the polygenic basis of atherosclerosis using disease associated cell state signatures

2022-06-24

Abstract excerpt

<title>Abstract</title> <p>Coronary artery disease (CAD) is a pandemic disease where up to half of the risk is explained by genetic factors. Advanced insights into genetic basis of CAD require deeper understanding of the contributions of different cell types, molecular pathways and genes to disease heritability. Here, we investigate the biological diversity of atherosclerosis associated cell states and interrogat...

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Literature Corpus work: 10bb7ce1-7807-5a28-b290-510d5ac40239
DOI: 10.21203/rs.3.rs-1775130/v1

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