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An efficient and robust tool for colocalisation: Pair-wise Conditional and Colocalisation (PWCoCo)

2022-08-08

Abstract excerpt

Genetic colocalisation is an important tool to test for shared genetic aetiology and is commonly used to strengthen causal inference in genetic studies of molecular traits and drug targets. However, the single causal variant assumption of the original colocalization method is a considerable limitation in genomic regions with multiple causal effects. We integrated conditional analyses (GCTA-COJO) and colocalisation...

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Literature Corpus work
f8b60192-3272-5bbd-8c51-2c53e3e53f1f
DOI
10.1101/2022.08.08.503158
Open publication

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An efficient and robust tool for colocalisation: Pair-wise Conditional and Colocalisation (PWCoCo)DOI 10.1101/2022.08.08.503158
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