Article
COLOCdb: a comprehensive resource for multi-model colocalization of complex traits.
Nucleic acids research - 5 Jan 2024
Pan Siyu, Kang Hongen, Liu Xinxuan, Li Shuhua, Yang Peng, Wu Mingqiu, Yuan Na, Lin Shiqi, Zheng Qiwen, Jia Peilin
Abstract excerpt
Large-scale genome-wide association studies (GWAS) have provided profound insights into complex traits and diseases. Yet, deciphering the fine-scale molecular mechanisms of how genetic variants manifest to cause the phenotypes remains a daunting task. Here, we present COLOCdb (https://ngdc.cncb.ac.cn/colocdb), a comprehensive genetic colocalization database by integrating more than 3000 GWAS summary statistics...
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