Ultra-fast genetic colocalisation across millions of association signals.

Abstract excerpt

Co localisation is a powerful approach to assess if two genetic association signals are likely to share a causal variant. However, association analyses in large bio banks and molecular quantitative trait loci (molmol) studies now routinely identify millions of association signals across thousands of traits, making it infeasible to test for colocalization between all pairs of signals. Here we introduce gpu-coloc,...

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