SharePro: an accurate and efficient genetic colocalization method accounting for multiple causal signals.

Abstract excerpt

MOTIVATION: Colocalization analysis is commonly used to assess whether two or more traits share the same genetic signals identified in genome-wide association studies (GWAS), and is important for prioritizing targets for functional follow-up of GWAS results. Existing colocalization methods can have suboptimal performance when there are multiple causal variants in one genomic locus. RESULTS: We propose SharePro to...

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• Share to Algorithms
• Share to Bone Density
• Share to Genome-Wide Association Study