Article

Estimating colocalization probability from limited summary statistics

2020-05-22

Abstract excerpt

1 1.1 <h4>Motivation</h4> A common approach to understanding the mechanisms of noncoding GWAS associations is to test the GWAS variant for association with lower level cellular phenotypes such as gene expression. However, significant association to gene expression will often arise from linkage disequilibrium to a separate causal variant and be unrelated to the mechanism underlying the GWAS association. Colocaliza...

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Literature Corpus work: 25298365-564f-5091-864b-f30bb2619145
DOI: 10.1101/2020.05.19.104927

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