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Article

Estimating colocalization probability from limited summary statistics.

BMC bioinformatics - 17 May 2021

King Emily A, Dunbar Fengjiao, Davis Justin Wade, Degner Jacob F

Abstract excerpt

BACKGROUND: Colocalization is a statistical method used in genetics to determine whether the same variant is causal for multiple phenotypes, for example, complex traits and gene expression. It provides stronger mechanistic evidence than shared significance, which can be produced through separate causal variants in linkage disequilibrium. Current colocalization methods require full summary statistics for both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34000989
DOI: 10.1186/s12859-021-04170-z
PMCID: PMC8130535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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