Article

Genetic Basis of Alternative Polyadenylation is an Emerging Molecular Phenotype for Human Traits and Diseases

2019-03-06

Abstract excerpt

<h4>SUMMARY</h4> Genome-wide association studies have identified thousands of non-coding variants that are statistically associated with human traits and diseases. However, functional interpretation of these variants remains a major challenge. Here, we describe the first atlas of human 3’ -UTR alternative polyadenylation (APA) Q uantitative T rait L oci (3’QTLs), i.e. ∼0.4 million genetic variants associated...

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Literature Corpus work: f8930288-dc21-5d7c-9e50-528165cae793
DOI: 10.1101/570176

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