Article

Impact of Rare Non-coding Variants on Human Diseases through Alternative Polyadenylation Outliers

2024-03-07

Abstract excerpt

<title>Abstract</title> <p>Although rare non-coding variants (RVs) play crucial roles in human complex traits and diseases, understanding their functional mechanisms and identifying those most closely associated with diseases continue to be major challenges. Here, we constructed the first comprehensive atlas of alternative polyadenylation (APA) outliers (aOutliers) from 15,201 samples across 49 human tissues. Str...

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Literature Corpus work: 4a3823e7-c37e-5ee7-b1ed-b34b04cc74a8
DOI: 10.21203/rs.3.rs-3907149/v1

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