Article

Attractor Landscape Analysis Distinguishes Aging Markers from Rejuvenation Targets in Human Keratinocytes

2026-02-03

Abstract excerpt

Cellular aging is characterized by progressive changes in gene expression that contribute to tissue dysfunction; however, identifying genes that regulate the aging process, rather than merely serve as biomarkers, remains a significant challenge. Here we present PRISM (Pseudotime Reversion via In Silico Modeling), a computational pipeline that integrates pseudotime trajectory analysis with Boolean network analysis...

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Literature Corpus work: f78ce851-003d-5ba2-9329-5ab78be60edc
DOI: 10.64898/2026.02.01.703159

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