Article
Identifying regulators of aged fibroblast activation in 3D tissue models
2025-02-11
Abstract excerpt
Robust 3D tissue culture models to activate aged fibroblasts for cell-based therapies and identify regulators of such activation are still missing. In our previous study, we showed that aged fibroblasts can be activated simply through applying compressive force, without the need for exogenous factors, leading to increased migration. In this study, we develop a pipeline to evaluate the role of specific pharmacologi...
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Identifiers and source
- Literature Corpus work
- 49116f91-9e99-5501-aca8-090815045329
- DOI
- 10.1101/2025.02.10.636275