Article

Predicting how perturbations reshape cellular trajectories with PerturbGen

2026-03-05

Abstract excerpt

A major challenge in biology is predicting how cells transition between states over time and how perturbations disrupt these transitions. Understanding such dynamics is critical for identifying interventions that reverse pathological programs or reprogram cells toward desired states. Although recent computational approaches can predict single-cell perturbation responses in silico , they cannot predict responses a...

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Literature Corpus work: 4f08b634-93bc-5129-96c5-7c8c32e84f80
DOI: 10.64898/2026.03.04.709254

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