Article

Pasta, a versatile transcriptomic clock, maps the chemical and genetic determinants of aging and rejuvenation

2025-06-04

Abstract excerpt

With the growing burden of age-related diseases, understanding and modulating the aging process has become a priority. Transcriptomic aging clocks (TACs) can track biological age but remain limited by platform dependence, tissue specificity, or restricted accessibility. To address this, we developed Pasta, a robust and broadly applicable human TAC built using a novel ‘age-shift’ learning framework. Pasta accuratel...

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Literature Corpus work: fa36f05d-746c-5fab-af36-bcbcb5b94029
DOI: 10.1101/2025.06.04.657785

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