Article

Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer

2020-09-22

Abstract excerpt

<h4>ABSTRACT</h4> Single-cell epigenomic assays have tremendous potential to illuminate mechanisms of transcriptional control in functionally diverse cancer cell populations. However, application of these techniques to clinical tumor specimens has been hampered by the current inability to distinguish malignant from non-malignant cells, which potently confounds data analysis and interpretation. Here we describe Co...

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Literature Corpus work: f747ce4f-00ca-53ff-901d-0b176a744dd3
DOI: 10.1101/2020.09.21.305516

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