Article

Multimodal integration of single cell ATAC-seq data enables highly accurate delineation of clinically relevant tumor cell subpopulations

2024-10-12

Abstract excerpt

Accurately deciphering tumor cellular heterogeneity is crucial for developing effective treatments. While single-cell epigenomics assays offer powerful insights into studying tumor heterogeneity beyond the transcriptional level, their application remains a significant challenge. To address this, we introduce Multimodal-based Analysis of scATAC-Seq data (MAAS), a method designed to identify functional tumor cell su...

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Literature Corpus work: dd772df6-ee3b-536b-9374-e14f7ebeba98
DOI: 10.1101/2024.10.11.617736

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