Article

Signatures of copy number alterations in human cancer

2021-04-30

Abstract excerpt

<h4>ABSTRACT</h4> The gains and losses of DNA that emerge as a consequence of mitotic errors and chromosomal instability are prevalent in cancer. These copy number alterations contribute to cancer initiaition, progression and therapeutic resistance. Here, we present a conceptual framework for examining the patterns of copy number alterations in human cancer using whole-genome sequencing, whole-exome sequencing, a...

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Literature Corpus work: 94685668-34ae-5b76-b7b8-dbc466d5d239
DOI: 10.1101/2021.04.30.441940

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