Article

A Bayesian method to cluster single-cell RNA sequencing data using Copy Number Alterations

2021-02-03

Abstract excerpt

<h4>Motivation</h4> Cancers are composed by several heterogeneous subpopulations, each one harbouring different genetic and epigenetic somatic alterations that contribute to disease onset and therapy response. In recent years, copy number alterations leading to tumour aneuploidy have been identified as potential key drivers of such populations, but the definition of the precise makeup of cancer subclones from seq...

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Literature Corpus work: 91c6cb64-ce2d-5d22-bc91-1d65a75a0fdc
DOI: 10.1101/2021.02.02.429335

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