Article

The peptide binding specificity of the inhibitory and activating KIR2D receptors

2015-01-01

Abstract excerpt

Human natural killer (NK) cells play an invaluable role in the first line of innate immune defence against viral infection and cancer. They are the main sub-group of lymphocytes with predominant expression of polymorphic KIR (Killer-immunoglobulin-like-receptors), which allows them to engage with their MHC Class I ligands. Past immunogenetic analysis has shown that possession of KIR2DL3 may confer an advantage in...

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Literature Corpus work: f6ec09f5-d19f-54dc-9011-3daa353b1fb5
DOI: 10.25560/27222

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