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Article

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

Clinical immunology (Orlando, Fla.) - 1 Oct 2010

Gao Xuejun, Jiao Yulian, Wang Laicheng, Liu Xiaowen, Sun Wenping, Cui Bin, Chen Zijiang, Zhao Yueran

Abstract excerpt

Antiviral activity of natural killer (NK) cells is regulated partially through inhibitory and activating killer cell immunoglobulin-like receptors (KIR) interacting with human leukocyte antigen C (HLA-C) ligands. The highly polymorphic nature of HLA-C and KIR genes endows individuals with diverse HLA-C/KIR combinations, which may confer susceptibility to or protection against a certain challenge. We analyzed the...

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Identifiers

PMID: 20643584
DOI: 10.1016/j.clim.2010.05.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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