Article

Innate receptors with high specificity for HLA class I–peptide complexes

2023-02-06

Abstract excerpt

<h4>Summary</h4> Genetic studies associate killer-cell immunoglobulin-like receptors (KIR) and their HLA class I ligands with a variety of human diseases. The basis for these associations, and the relative contribution of inhibitory and activating KIR to NK cell responses are unclear. As KIR binding to HLA-I is peptide-dependent, we performed systematic screens totaling over 3,500 specific interactions to determi...

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Literature Corpus work: b83bee61-d68f-563d-bf6d-0ac9cd0060df
DOI: 10.1101/2023.02.06.527249

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