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Article

Allelic variation in KIR2DL3 generates a KIR2DL2-like receptor with increased binding to its HLA-C ligand.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2013

Frazier William R, Steiner Noriko, Hou Lihua, Dakshanamurthy Sivanesan, Hurley Carolyn Katovich

Abstract excerpt

Although extensive homology exists between their extracellular domains, NK cell inhibitory receptors killer Ig-like receptor (KIR) 2DL2*001 and KIR2DL3*001 have previously been shown to differ substantially in their HLA-C binding avidity. To explore the largely uncharacterized impact of allelic diversity, the most common KIR2DL2/3 allelic products in European American and African American populations were...

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Identifiers

PMID: 23686481
DOI: 10.4049/jimmunol.1300464
PMCID: PMC3679298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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