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Article

Peptide-specific engagement of the activating NK cell receptor KIR2DS1.

Scientific reports - 25 May 2017

Chapel Anaïs, Garcia-Beltran Wilfredo F, Hölzemer Angelique, Ziegler Maja, Lunemann Sebastian, Martrus Gloria, Altfeld Marcus

Abstract excerpt

The activating NK cell receptor KIR2DS1 has been shown to be involved in many disorders including autoimmune diseases, malignancies and pregnancy outcomes. However, the precise ligands and functions of this receptor remain unclear. We aimed to gain a better understanding of the factors involved in the binding of KIR2DS1 and its inhibitory counterpart KIR2DL1 to HLA class I molecules, and the consequences for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28546555
DOI: 10.1038/s41598-017-02449-x
PMCID: PMC5445099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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