Article

Somatic whole genome dynamics of precancer in Barrett’s Esophagus

2021-03-02

Abstract excerpt

<title>Abstract</title> <p>While the genomes of normal tissues undergo dynamic changes over time, little is understood about the temporal-spatial dynamics of genomes in premalignant tissues that progress to cancer compared to those that remain cancer-free. Here we use whole genome sequencing to contrast genomic alterations in 427 longitudinal samples from 40 patients with stable Barrett’s esophagus compared to 40...

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Literature Corpus work: f57ce37d-6c9c-5deb-8f6c-0351e464a2cd
DOI: 10.21203/rs.3.rs-257949/v1

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