Article
Assessment of Esophageal Adenocarcinoma Risk Using Somatic Chromosome Alterations in Longitudinal Samples in Barrett's Esophagus.
Cancer prevention research (Philadelphia, Pa.) - 1 Sept 2015
Li Xiaohong, Paulson Thomas G, Galipeau Patricia C, Sanchez Carissa A, Liu Karen, Kuhner Mary K, Maley Carlo C, Self Steven G, Vaughan Thomas L, Reid Brian J, Blount Patricia L
Abstract excerpt
Cancers detected at a late stage are often refractory to treatments and ultimately lethal. Early detection can significantly increase survival probability, but attempts to reduce mortality by early detection have frequently increased overdiagnosis of indolent conditions that do not progress over a lifetime. Study designs that incorporate biomarker trajectories in time and space are needed to distinguish patients...
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