Article

Glial activation mediates phenotypic effects of<i>APOEε4</i>and sex in Alzheimer’s disease

2024-03-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> This study examined the impact of apolipoprotein ɛ4 ( APOEɛ4 ) allele frequency and sex on the phenotype of Alzheimer’s disease (AD). <h4>METHODS</h4> The baseline characteristics, CSF, and neuroimaging biomarkers, and cognition scores collected from 45 patients aged 50-74 years with confirmed early AD from clinical trial NCT03186989 were evaluated in a post-hoc study. <h4>R...

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Literature Corpus work: f4b66b90-745f-5da3-a595-ae26e6ebf4e2
DOI: 10.1101/2024.03.08.24303882

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