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Article

Differential Associations of APOEɛ2 and APOEɛ4 Genotypes with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Individuals Without Dementia.

Journal of Alzheimer's disease : JAD - 1 Jan 2023

Zhao Bing, Ou Ya-Nan, Zhang Xuan-Yue, Fu Yan, Tan Lan

Abstract excerpt

BACKGROUND: The APOE genotype has emerged as the major genetic factor for AD but differs among different alleles. OBJECTIVE: To investigate the discrepant effects of APOE genotype on AD cerebrospinal fluid (CSF) biomarkers. METHODS: A total of 989 non-demented ADNI participants were included. The associations of APOEɛ2 and APOEɛ4 with CSF biomarkers were investigated using linear regression models. Interaction...

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PMID: 38073392
DOI: 10.3233/JAD-230761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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