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Article

Differences in Alzheimer's Disease-Related Pathology Profiles Across Apolipoprotein Groups.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Feb 2024

Morrison Cassandra, Dadar Mahsa, Kamal Farooq, Collins D Louis

Abstract excerpt

The apolipoprotein (APOE) ɛ4 allele is a risk factor for Alzheimer's disease (AD), whereas the ɛ2 allele is thought to be protective against AD. Few studies have examined the relationship between brain pathologies, atrophy, white matter hyperintensities (WMHs) and APOE status in those with the ɛ2ɛ4 genotype and results are inconsistent for those with an ɛ2 allele. Alzheimer's disease neuroimaging participants...

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Identifiers

PMID: 37935216
DOI: 10.1093/gerona/glad254
PMCID: PMC10799756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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