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Impact of apolipoprotein E isoforms on sporadic Alzheimer’s disease

25 May 2023

Abstract excerpt

The impact of apolipoprotein E (ApoE) isoforms on sporadic Alzheimer's disease has long been studied; however, the influences of apolipoprotein E gene (APOE) on healthy and pathological human brains are not fully understood. ApoE exists as three common isoforms (ApoE2, ApoE3, and ApoE4), which differ in two amino acid residues. Traditionally, ApoE binds cholesterol and phospholipids and ApoE isoforms display...

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PMID: 37488848
DOI: 10.4103/1673-5374.375316

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