Article

Onset of Alzheimer disease in apolipoprotein ɛ4 carriers is earlier in butyrylcholinesterase K variant carriers

2024-01-03

Abstract excerpt

<h4>Background</h4> We wished to examine the impact of the K-variant of butyrylcholinesterase ( BCHE-K ) carrier status on age-at-diagnosis of Alzheimer disease (AD) in APOE4 carriers. <h4>Methods</h4> In 45 patients, aged 50-74 years, with cerebrospinal fluid (CSF) biomarker confirmed mild AD, recruited into a clinical trial ( NCT03186989 ), baseline demographics, disease characteristics, and biomarkers were eval...

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Literature Corpus work: 6cbc990c-7691-5a0f-9c9e-35786ef6ae3c
DOI: 10.1101/2024.01.02.24300718

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