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Article

Sex influences the effects of APOE genotype and Alzheimer’s diagnosis on neuropathology and memory

2020-06-26

Abstract excerpt

Alzheimer’s disease (AD) is characterised by severe cognitive decline and pathological changes in the brain (brain atrophy, hyperphosphorylation of tau, and deposition of toxic amyloid-beta protein). Females have greater neuropathology (AD biomarkers and brain atrophy rates) and cognitive decline than males, however these effects can depend on diagnosis (amnestic mild cognitive impairment (aMCI) or AD) and APOE ge...

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Literature Corpus work
6581bc61-f75d-5934-8e8d-c3f071c01f60
DOI
10.1101/2020.06.25.20139980
Open publication

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Sex influences the effects of APOE genotype and Alzheimer’s diagnosis on neuropathology and memoryDOI 10.1101/2020.06.25.20139980
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