Article

Selective deletion of <i>Methyl CpG binding protein 2</i> from parvalbumin interneurons in the auditory cortex delays the onset of maternal retrieval in mice

2023-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome. MECP2 codes for methyl CpG binding protein 2 (MECP2), a transcriptional regulator that activates genetic programs for experience-dependent plasticity. Many neural and behavioral symptoms of Rett syndrome may result from dysregulated timing and threshold for plasticity. As a model of adult plasticity, we examine changes to...

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Literature Corpus work: f3fb2cc9-70df-5e3d-9ebd-6baa1b0db69e
DOI: 10.1101/2023.01.30.526321

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Selective deletion of <i>Methyl CpG binding protein 2</i> from parvalbumin interneurons in the auditory cortex delays the onset of maternal retrieval in miceDOI 10.1101/2023.01.30.526321Read

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