Article

Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation

2023-12-15

Abstract excerpt

<h4>ABSTRACT</h4> The 800 million human infections with SARS-CoV-2 and the likely emergence of new variants and additional coronaviruses necessitate a better understanding of the essential spike glycoprotein and the development of immunogens that foster broader and more durable immunity. The S2 fusion subunit is more conserved in sequence, is essential to function, and would be a desirable immunogen to boost broa...

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Literature Corpus work: f3f9c133-d7d6-5bb3-8409-faa4d89f3d29
DOI: 10.1101/2023.12.14.571764

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