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Article

Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes.

Neurology - 28 Jul 2020

Georgakis Marios K, Gill Dipender, Webb Alastair J S, Evangelou Evangelos, Elliott Paul, Sudlow Cathie L M, Dehghan Abbas, Malik Rainer, Tzoulaki Ioanna, Dichgans Martin

Abstract excerpt

OBJECTIVE: We employed Mendelian randomization to explore whether the effects of blood pressure (BP) and BP-lowering through different antihypertensive drug classes on stroke risk vary by stroke etiology. METHODS: We selected genetic variants associated with systolic and diastolic BP and BP-lowering variants in genes encoding antihypertensive drug targets from genome-wide association studies (GWAS) on 757,601...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32611631
DOI: 10.1212/WNL.0000000000009814
PMCID: PMC7455321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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