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Hypertension and Dementia: A Mendelian Randomisation Study Assessing Potential Causal Relationships with All-Cause Dementia, Alzheimer’s Disease and Vascular Dementia in the UK Biobank

2025-03-13

Abstract excerpt

Hypertension is a key modifiable risk factor for longevity. However, evidence linking hypertension to dementia remains inconsistent, potentially due to subtype-specific effects. We aimed to examine relationships between systolic blood pressure (SBP) and risk of Alzheimer’s disease (AD) and vascular dementia (VaD) using individual-level Mendelian randomization (MR) analyses. Logistic and Cox regressions assessed th...

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Literature Corpus work: 652366d5-e4de-55ad-ac45-30998d7df0b0
DOI: 10.1101/2025.03.12.25323830

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