Article

Distinct aneuploid karyotypes are universally selected for across cancers

2025-07-30

Abstract excerpt

Aneuploid karyotype evolution leads to immense variability in cancer patient prognosis, so characterizing relevant trends has been an important objective (1–9). Recurrent chromosome gains and losses as well as oncogenic mutations have been associated with specific cancers (10–14), but a general trend in aneuploidy evolution has not yet been identified. Here we show a universal selection principle for karyotypes co...

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Literature Corpus work: efbe6d6a-0eb0-51ee-9541-36a897a6a1a9
DOI: 10.1101/2025.07.25.666795

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