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Article

On the karyotypic origin and evolution of cancer cells.

Cancer genetics and cytogenetics - 15 Oct 2009

Nicholson Joshua M, Duesberg Peter

Abstract excerpt

Cancers have clonal, aneuploid karyotypes that evolve ever more malignant phenotypes spontaneously. Because these facts are hard to explain by conventional mutation theory, we propose here a karyotypic cancer theory. According to this theory, carcinogens initiate carcinogenesis by inducing random...

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Identifiers

PMID: 19781442
DOI: 10.1016/j.cancergencyto.2009.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19781442-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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