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Genetically modified IL-2 bone marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment

2022-10-21

Abstract excerpt

<h4>ABSTRACT</h4> Gliomas are the most prevalent type of brain tumors and one of the leading causes of cancer-related death in the adolescent and young adult population (AYA). Two-thirds of glioma AYA patients are affected by low-grade gliomas (LGGs), but there are no specific treatments. Therefore, a percentage of LGG patients experience tumor relapse and malignant progression to high-grade glioma which leads to...

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Literature Corpus work
edf1acd5-54cc-5af2-8bdc-4e577ce05fb6
DOI
10.1101/2022.10.19.511786
Open publication

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Genetically modified IL-2 bone marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironmentDOI 10.1101/2022.10.19.511786
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