Article
Immune Microenvironment Landscape in CNS Tumors and Role in Responses to Immunotherapy.
Cells - 9 Aug 2021
Najem Hinda, Khasraw Mustafa, Heimberger Amy B
Abstract excerpt
Despite the important evolution of immunotherapeutic agents, brain tumors remain, in general, refractory to immune therapeutics. Recent discoveries have revealed that the glioma microenvironment includes a wide variety of immune cells in various states that play an important role in the process of tumorigenesis. Anti-tumor immune activity may be occurring or induced in immunogenic hot spots or at the invasive...
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