Article

Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14

2026-05-13

Abstract excerpt

Glioblastomas are incurable and lethal brain cancers. Immunotherapies offer new and promising treatment options for glioblastoma patients, but the highly immunosuppressive nature of these cancers presents a challenging clinical obstacle. Glioblastoma immune evasion is driven by cell-cell interactions in the tumor microenvironment and recent studies have identified astrocytes as important contributors to immune sil...

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Literature Corpus work: ffb93426-fbf4-5830-8dea-de37c18d88f1
DOI: 10.64898/2026.05.10.724074

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