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Revealing the role of SPP1+ macrophages in glioma prognosis and therapeutic targeting by investigating tumor-associated macrophage landscape in grade 2 and 3 gliomas

21 Mar 2024

Abstract excerpt

BACKGROUND: Glioma is a highly heterogeneous brain tumor categorized into World Health Organization (WHO) grades 1-4 based on its malignancy. The suppressive immune microenvironment of glioma contributes significantly to unfavourable patient outcomes. However, the cellular composition and their complex interplays within the glioma environment remain poorly understood, and reliable prognostic markers remain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38515213
DOI: 10.1186/s13578-024-01218-4

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