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Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity and Restricted Cytotoxic Effector Cell Trafficking and Activation During Malignant Progression in Glioma

2021-09-25

Abstract excerpt

<h4>ABSTRACT</h4> Low grade gliomas (LGG) account for about two-thirds of all glioma diagnoses in adolescents and young adults (AYA) and malignant progression of these patients leads to dismal outcomes. Recent studies have shown the importance of the dynamic tumor microenvironment in high-grade gliomas (HGG ), yet its role is still poorly understood in low-grade glioma malignant progression. Here, we investigat...

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Literature Corpus work: f65c22de-48d4-5900-b787-976467fb6865
DOI: 10.1101/2021.09.24.461735

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