Article

Tissue-Specific and NF-kappaB-Independent Xist RNA Localization Patterns in Female Intestinal, Blood, and Muscle Progenitors

2025-09-02

Abstract excerpt

<h4>ABSTRACT</h4> X-Chromosome Inactivation (XCI), driven by the expression of Xist RNA and the enrichment of various repressive epigenetic marks, results in the formation of a mostly inactive X chromosome (Xi) to equalize X-linked gene expression between sexes. Unexpectedly, in unstimulated female lymphocytes that are largely quiescent, these epigenetic features are largely absent but are restored by NF-κB signa...

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Literature Corpus work: ebec0a69-ad5c-533a-839c-a3d800b04c42
DOI: 10.1101/2025.08.30.673230

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