Article

Coding and noncoding somatic mutations in basal cell carcinoma

2019-10-16

Abstract excerpt

Basal cell carcinoma (BCC) represents the most commonly diagnosed human cancer among persons of European ancestry with etiology mainly attributed to sun-exposure. In this study we investigated mutations in coding and flanking regions of the PTCH1 and TP53 genes and noncoding alterations in the TERT and DPH3 promoters in 191 BCC tumors. In addition, we measured CpG methylation within the TERT hypermethylated o...

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Literature Corpus work: eba7474a-6889-5e56-86ef-a6bf6a1c8747
DOI: 10.1101/807313

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