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Article

Molecular alterations in basal cell carcinoma subtypes.

Scientific reports - 24 Jun 2021

Di Nardo Lucia, Pellegrini Cristina, Di Stefani Alessandro, Ricci Francesco, Fossati Barbara, Del Regno Laura, Carbone Carmine, Piro Geny, Corbo Vincenzo, Delfino Pietro, De Summa Simona, Maturo Maria Giovanna, Rocco Tea, Tortora Giampaolo, Fargnoli Maria Concetta, Peris Ketty

Abstract excerpt

A number of genes have been implicated in the pathogenesis of BCC in addition to the Hedgehog pathway, which is known to drive the initiation of this tumour. We performed in-depth analysis of 13 BCC-related genes (CSMD1, CSMD2, DPH3 promoter, PTCH1, SMO, GLI1, NOTCH1, NOTCH2, TP53, ITIH2, DPP10, STEAP4, TERT promoter) in 57 BCC lesions (26 superficial and 31 nodular) from 55 patients and their corresponding blood...

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Identifiers

PMID: 34168209
DOI: 10.1038/s41598-021-92592-3
PMCID: PMC8225846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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