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Article

TERT promoter mutations in skin cancer: the effects of sun exposure and X-irradiation.

The Journal of investigative dermatology - 1 Aug 2014

Pópulo Helena, Boaventura Paula, Vinagre João, Batista Rui, Mendes Adélia, Caldas Regina, Pardal Joana, Azevedo Filomena, Honavar Mrinalini, Guimarães Isabel, Manuel Lopes José, Sobrinho-Simões Manuel, Soares Paula

Abstract excerpt

The reactivation or reexpression of telomerase (TERT) is a widespread feature of neoplasms. TERT promoter mutations were recently reported that were hypothesized to result from UV radiation. In this retrospective study, we assessed TERT promoter mutations in 196 cutaneous basal cell carcinomas (BCCs), including 102 tumors from X-irradiated patients, 94 tumors from patients never exposed to ionizing radiation...

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Share to Carcinoma, Basal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

Share to Proportional Hazards Models

Share to Skin Neoplasms

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Source

Identifiers

PMID: 24691053
DOI: 10.1038/jid.2014.163

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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