Article
Role of PTCH and p53 genes in early-onset basal cell carcinoma.
The American journal of pathology - 1 Feb 2001
Zhang H, Ping X L, Lee P K, Wu X L, Yao Y J, Zhang M J, Silvers D N, Ratner D, Malhotra R, Peacocke M, Tsou H C
Abstract excerpt
Basal cell carcinoma (BCC) is the most common skin cancer in the Western world. Ultraviolet (UV) exposure, race, age, gender, and decreased DNA repair capacity are known risk factors for the development of BCC. Of these, UVB irradiation from sunlight is the most significant risk factor. The incidence of sporadic BCC increases in individuals older than age 55, with the greatest incidence reported in individuals...
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